Vitamin E May Elecate The Risk Of Some Cancers

+1 by casmhar , Elecate= Elevate? nes pas?

durp

-1 by meepuall , POS study -1 by wotak , foil hat cancer studies anger me

it's well known that taking large amounts of some vitamins or minerals, such as iron, can lead to ill health and even death.

what, exactly, is alarmist or meepty about this particular study?

meepty?

From the abstract.. Methods: Prospective cohort of 77,721 men and women aged 50'76 years from Washington State in the VITAL (VITamins And Lifestyle) study. Cases were identified through the Seattle'Puget Sound SEER (Surveillance, Epidemiology, and End Results) cancer registry.

Measurements and Main Results: Hazard ratios (HRs) for incident lung cancer according to 10-year average daily use of supplemental multivitamins, vitamin C, vitamin E, and folate. A total of 521 cases of lung cancer were identified. Adjusting for smoking, age, and meep, there was no inverse association with any supplement. Supplemental vitamin E was associated with a small increased risk of lung cancer (HR, 1.05 for every 100-mg/d increase in dose; 95% confidence interval [CI], 1.00'1.09; P = 0.033). This risk of supplemental vitamin E was largely confined to current smokers (HR, 1.11 for every 100-mg/d increase; 95% CI, 1.03'1.19; P < 0.01) and was greatest for non'small cell lung cancer (HR, 1.07 for every 100-mg/d increase; 95% CI, 1.02'1.12; P = 0.004).

Conclusions: Supplemental multivitamins, vitamin C, vitamin E, and folate were not associated with a decreased risk of lung cancer. Supplemental vitamin E was associated with a small increased risk. Patients should be counseled against using these supplements to prevent lung cancer.

May elevate yes, but smoking is the primary causal agent here. Also the pill poppers in the study weren't controlled for other health/risk factors besides age, meep and smoking--what about health and dietary habits? We are talking supplements here, I bet we can ask about alimentary routines and how those work and turn this into a dietary study not a pulmonary cancer study which may be more interesting.

Also vitamin E is fat soluble, so this could mean that there is something else at work--which is really beyond the scope of the 'old people smoking popping pills' research we are talking about here. I don't think it's tin foil or terribly flawed, but not the best out there and at best directional. The reporter leaves out the 'minor risk' part and choses 'risk' which is misleading.

Google Trends 'Elecate' spikes for some reason this week...

Exactly! Thanks Phil - well said

Also vitamin E is fat soluble, so this could mean that there is something else at work--which is really beyond the scope of the 'old people smoking popping pills' research we are talking about here. I don't think it's tin foil or terribly flawed, but not the best out there and at best directional. The reporter leaves out the 'minor risk' part and choses 'risk' which is misleading.

you're kind of right

Excess Dietary Vitamin E Lowers the Activities of Antioxidative Enzymes in Erythrocytes of Rats Fed Salmon Oil

vitamin E might be blocking the effects of omega 3 fatty acids, which are widely known to be extremely beneficial.

besides, the article says 'might' increase the risk of one type of cancer. this is not yellow journalism by any stretch of the definition.

the study is sound. you don't like the fact that there aren't controls, but we don't have controlled studies on smoking, and you accept that smoking increases the risk of lung cancer, no?

yeah smoking is bad for cancer of the lungs and some others too--the study though would be more interesting if they talked about Vitamin E and the other factors it has in relationship to OTHER antioxidant, etc. dietary intakes--if only we knew what the old pill poppers ate, how much they weighed, how often they exercised we could slice the data and show that of the Vitamin E group there were subsets and whatnot.

oh well there will be research I am sure.